Lethathamo la litaba tse ka hare ho sengoloa sena:
1. Nts'etsopele ea Amino acid
2. Litlatsetso tsa sebopeho
3. Meetso ea lik'hemik'hale
4.Classifiting
5. Synthesis
6. Thepa ea Leano la Leafsicochemical
7. Ho chefo
8. Ketsahalo ea Antimicrolish
9. Meruti ea Rheology
10. Likopo ka indasteri ea litlolo
11. Likopo ka litlolo tsa letsatsi le letsatsi
Amino acid surfactats (as)Na sehlopha sa lits'ila tse thehiloeng ka ho kopanya lihlopha tsa hydrophobic tse nang le amino acid e le 'ngoe kapa ho feta. Tabeng ena, Amino acid a amino a ka ba le lefu la liprotheine kapa mehloli e tšoanang. Letlapa lena le akaretsa lintlha tsa litsela tse ngata tse fumanehang tsa AAS bakeng sa litsela tse fapaneng tsa li-as tsa lihlahisoa tsa ho qetela, ho kenyeletsa le botsitso, ho tsitsipana le boqapi le bofokoli ba biodera. E le sehlopha sa li-surfactats ka tlhoko e ntseng e eketseha, ho feto-fetoha ha AAS ka lebaka la sebopeho sa tsona se fapaneng ho fana ka mangolo a mangata a khoebo.
Ha ba fuoa hore li-surfactal li sebelisoa hohle ho seriti, emmorigis, lisuli tsa oli le meriana, bafuputsi ba se ke ba khaotsa ho ela hloko li-surfaman.
Lihlahisoa tse kholo ke lihlahisoa tsa lik'hemik'hale tse jeoang ka nako e le ngoe letsatsi le letsatsi ho potoloha lefatše mme li bile le phello e mpe tikolohong ea metsi a santia.Boithuto bo bontšitse hore tšebeliso ea liphoofolo tse ngata e ka ba le phello e mpe tikolohong.
Kajeno, lino tse seng chefo, biodegraphy le biocompipt li batla li le bohlokoa ho bareki e le ts'ebetso le ts'ebetso ea li-surfactats.
BiosurFanments ke li-mifsax tse ntle tsa tikoloho tseo ka tlhaho li hlahisoang ke likokoana-hloko tse kang libaktheria, li-fungus le tomoso kapa tsa sephiri.Therefore, biosurfactants can also be prepared by molecular design to mimic natural amphiphilic structures, such as phospholipids, alkyl glycosides and acyl Amino Acids.
Amino acid surfactats (as)ke e 'ngoe ea li-surfactats tse tloaelehileng, hangata li hlahisoa ka thepa e tala kapa ea setsomi. Boholo ba mashome a mabeli a fetileng, Maas o hohetse lithahasello tse ngata ho tsa lisebelisoa tse ngata, eseng hobane li ka ba boloke tikoloho.
Li-AAS li ka hlalosoa e le sehlopha sa li-amino tse nang le li-acid tse nang le li-acid tse nang le li-acid tse nang le li-acid (ho 2 c-Chre-n Libaka tse 2 tse sebetsang tsa Amino acid li lumella ho tlisoa ke mefuta e fapaneng ea lijalo tse fapaneng. Kakaretso ea Amono acid e 20 e tsejoang e teng ka tlhaho mme o ikarabelle bakeng sa maikutlo ohle a mmele le mesebetsing ea bophelo. Li fapana le e mong le e mong feela ho ea ka masala r (setšoantšo sa 1, pk a ke logarithm e mpe ea acid acid acist acid acist acired afst ona). Tse ling ke polarrophobic, tse ling li na le polar le hydrophilic, tse ling ke tsa mantlha ebile tse ling ke tsacidic.
Hobane Amono acid ke likhamphani tse ncha-peleng, li-surfactats tse hlophisitsoeng hantle ho Amino acid le tsona li na le monyetla o matla oa ho ba le kamano e matla le ea tikoloho. Sebopeho se bonolo le sa tlhaho, chefo e tlase le biodegramend e tlase hangata li ba etsa hore ba phahame ho isa ho li-surfactats tse tloaelehileng. U sebelisa lisebelisoa tse ncha tse nchafalitsoeng (mohlala, Amono acid le oli ea limela), MaA o ka hlahisoa ke litsela tse fapaneng tsa biotechnological le li-biilm.
Mathoasong a lekholo la bo20 la lilemo, acid e ile ea fumanoa pele ho sebelisoa e le likarolo tsa li-synthes tsa li-surfactats.Lia ka li ne li sebelisoa haholo e le li-pressives tse hlophisitsoeng ho pharmaconetical le litlolo.Ntle le moo, Maas a ile a fumanoa a le mafolofolo khahlanong le libaktheria tse fapaneng tse mpe, li-tumors le vaerase. Ka 1988, ho fumaneha ha a Maas a theko e tlase a AAS ho hlahiseng thato ea lipatlisiso mabapi le tšebetso e potolohileng. Kajeno, nts'etsopele ea biotechnology, acino acidu ea amino acired le eona e khona ho kenya letsoho khoebong e kholo ka tomoso e le nang le tikoloho haholoanyane.
01 Nts'etsopele ea Amino acid
Ha mathoasong a lekholo la bo19 la lilemo, ha ka tlhaho a acino acid a fumanoa ka lekhetlo la pele, meaho ea bona e boletsoe esale pele hore e bohlokoa haholo ea ho hlophisoa ha ampihla. Thuto ea pele ka li-syntthesis tsa AAS e tlalehiloe ke Bondi ka 1909.
Thutong eo, n-acylglycine le n-acylanune li ile tsa kenngoa ka lihlopha tsa hydrophilic bakeng sa li-surfactats. Mosebetsi o latelang o ne o ama semelo sa li-acid tsa lipoamino acino a sebelisa glycine le alane, le Henrich et al. e phatlalalitsoe letoto la se fumanoeng,Ho kenyelletsa ts'ebeliso ea pele ea patent, tšebeliso ea ACYL SarCosinate le Acyl Asparte letsoai e le litsi tsa lihlahisoa tsa ho hloekisa malapa (mohlala, li-shampoos, li-duthPastes).Kamora moo, bafuputsi ba bangata ba ile ba fuputsa thepa ea maiketsetso le ea physipical ea Acyl Acino acino acino acino. Ho fihla joale, ho hatisitsoe lingoliloeng tse ngata sesynthesis, thepa, lits'ebetso tsa indasteri le phetisetso ea biodegrada ea AAS.
02 Thepa ea sebopeho
Liketane tse seng tsa polai hydrophobic tse nang le mafura a li-as tsa AA li ka fapana ka sebopeho, bolelele ba ketane le palo.Phapang ea sebopeho le tšebetso e phahameng ea AAS e hlalosa mefuta ea tsona e pharalletseng le ea tlhaho le tlhaho ea tlhaho. Lihlopheng tsa lihlooho tsa AAS li entsoe ka amino acino acid kapa pppides. Phapang har'a lihlopha tsa lihlooho li khetholla ho thetsi, le tšebetso ea likokoana-hloko tsa limela tsena. Lihlopheng tse sebetsang sehlopheng sa hlooho ebe u tseba mofuta oa AAA, ho kenyelletsa le khau ea Aas, e ratanang le enisinic, e sa rateheng. Motsoako oa hydrophilic Acino acidic acidic le li-mongoana tsa litulo tsa hydrophobic li etsa sebopeho sa amppehHobilic tse etsang hore molek'hule e sebetse haholo. Ntle le moo, ho ba teng ha liathomo tsa carbon carbon ka molek'hule li thusa ho theha limolek'hule tsa chira.
03 Sebopeho sa lik'hemik'hale
Lihlahisoa tsohle tse pepeneneng le polypeptides ke lihlahisoa tsa polymerization tsa bana ba 20 α-Amino acid. Sehlopha sohle sa 20 α-Amino acid se na le sehlopha sa ts'ebetso ea carboxy Amino acid o fapana ho e mong ka lihlopha tse fapaneng tsa r-carbon (ntle le hydrogen.) Boholo le ho tefo, Alkality). Liphapang tsena li boetse li khetholla sello sa amino acid ka metsing.
Amino acid ke chiral (ntle le ea glycine) mme e sebetsa ka mokhoa o sebetsang ka tlhaho hobane ba na le sebaka se ntoeng se fapaneng se amanang le alpha carbon. Amino acid o na le mekhoa e 'meli e ka bang teng; Ha se litšoantšo tse se nang kelello tsa e mong, leha palo ea palo ea li-stereosiosimer e phahame haholo. R-GROUP e teng ho Amino acid (phenyanine The Acidic α-cook le basicides α-nh 2
R-cooh ↔r-coo-+ H+
R-nh3+↔r-nh2+ H+
Joalokaha ho bontšitsoe ho ionization etilibrium e kaholimo, Amino acid e na le bonyane lihlopha tse peli tsa acidic acidic; Leha ho le joalo, sehlopha sa carboyl se acidic haholo ha ho bapisoa le sehlopha sa li-amino o hlophisitsoeng. PH 7.4, sehlopha sa carboxyl se ikoahlaela ha sehlopha sa Amino se ntse se fanoa. Amino acid ka lihlopha tse sa khetholloang li sa nke lehlakore ka motlakase ph le foromo zwrity.
04 Classifice
AAS e ka khethoa ho latela litekanyetso tse 'ne, tse hlalosoang ka tlase le tsona.
4.1 Ho latela tšimoloho
| Ho latela tšimoloho, Maas a ka aroloa ka mekhahlelo e 2 eo ho latelang. ① Mokhahlelo oa tlhaho Metsoako e meng e etsahalang ka tlhaho e nang le Amino acid e boetse e na le bokhoni ba ho fokotsa khatello ea maikutlo / ho feta tekano, 'me ba bang ba feta ts'ebetso ea glycolieds. Ana a boetse a tsejoa e le lipoptides. Lipompopeides ke metsoako e tlase ea limela tsa tlhaho, hangata e hlahisoang ke mofuta oa bacillus.
Li-AAS tse joalo li arotsoe habeli ho feta:Surfackin, Iturn le Fengycin.
|
| Lelapa la li-pittides tse nang le mafolofolo li akaretsa li-Heptaperide tse fapaneng tsa lintho tse fapaneng,Joalokaha ho bontšitsoe ho Setšoantšo sa 2a, moo ho se nang li-c16 sa C12-C16 sa Hydrox se neng se hokahane le peptide. Pektide e nang le mafolofolo ke lakane ea macrocyclic eo ka eona reng e koetsoe ke catalysis pakeng tsa C-Terminus ea C-Fydroxy le pepene. Sebakeng sa Aururin, ho na le mefuta e tšeletseng ea sehlooho, Iturin a le C, MyCoubtilin le Bayoumycin D, F le L.Maemong ohle, li-heptapetides li hokahane le liketane tsa C14-C17 tsa FADTY li-acid tsa acid (liketane li ka fapana). Tabeng ea ekudimycin, sehlopha sa Amino sethaleng sa Amino se ka theha bonngoe ka c-terminus ka lebaka la sebopeho sa lactocyclic.
Sungycin e na le Fengycin A le B, e boetse e bitsoa Plipastatin ha Tyr9 ke D-E hlophisitsoe.Mokokotlo o hokahane le C14 -C18 Chain e nang le tšoaetso ea β-hydrous ea β-hydrous. Ha e hlaha, Plupastatin le eona ea macrocyclic, e nang le ketane ea maqeba a tyr le ho etsa sebopeho sa selikalikoe sa C-Terminal, ka hona ho etsa selikalikoe sa selikalikoe sa C-Terminal.
Ketsahalo ea synthetic AAS e ka boela ea tsamaisana le ho sebelisa acidic, ea mantlha ea acidic acidi acidic acino acidu acid le e sa jeleng paatino. Ho tloaelehile Amino acino e neng e sebelisoa bakeng sa li-as ke glutamis, Serrine, alinne, alane, le protheine hydrolysates. Ho sala le ho seha sebaka se ka lokisoa ke li-lik'hilomithara tse ngata, enzenmarmatic le ho chechisatic. Leha ho le joalo, bakeng sa tlhahiso ea AAA, Synthethes ea lik'hemik'hale e ka khona ho moruo. Mehlala e tloaelehileng e kenyelletsa n-laroryl-l-glutamic acid le n-palmitoyl-l-glutamic acid.
|
4.2 Ho ipapisitse le li-gang tse ntle tsa alivitotic
Ho ipapisitsoe le li-shōlleng sa li-alipiches, li-amino acid-acida li ka aroloa ka mefuta e 2.
Ho latela boemo ba sebaka sa npident
| Ho nkiloe AAS Metsoako e nkileng N-Amono e nkeloa sebaka ke sehlopha sa liporophilic kapa sehlopha sa carboyl, se fella ka ho lahleheloa ke matla. Mohlala o bonolo oa AAS o nkileng AAS o atino acino acino a acino a mabala a n-aino. N-DIPPURED AAAS e na le tlamahano ea sebaka se kopaneng pakeng tsa likarolo tsa hydrophobic le hydrophilic. Tlamo ea lapeng e na le bokhoni ba ho theha tlamo ea hydrojen, e lekang khanyetsong ea sirfactant ena tikolohong ea acid, ka hona e e etsa li-biodegramente.
Ho nkiloe AAS Likomileng tsa C-Ntla, ho nka karolo ho etsahala sehlopheng sa carboxyl (ka motsoako o mong kapa oa Ester. Metsoako e tloaelehileng ea c-e kentsoe (mohlala, ba bang kapa ba atamelang
③n- le c-e nkileng AAS Ka mofuta ona oa phatsime, lihlopha tsa li-amino le carboxyl ke karolo ea hydrophilic. Mofuta ona ha e le hantle ke ntho e ntle ka ntle. |
4.3 Ho latela palo ea mehatla ea hydrophobic
Ho ipapisitsoe le palo ea lihlopha tsa lihlooho le meharo ea hydrophobic, AA e ka aroloa ka lihlopha tse 'ne. Chain AAS, Gemini (Dimemini (Dimeni Li-surfactats tse otlolohileng li na le li-amino acid tse nang le mohatla o le mong oa hydrophobic feela (setšoantšo sa 3). Mofuta oa Gemini AAS o na le lihlopha tse peli tsa hlooho tse peli le mehatla e 'meli ea hydrophobic ka molek'hule (Setšoantšo sa 4). Ka mofuta ona oa sebopeho, ketane e 'meli e otlolohileng e hokahane hammoho ke sethala' me ka hona e bitsoa chelete. Ka lehlakoreng le leng, mofuta oa AAS oa Glycerolitipiti Li-surfactant tsena li ka nkoa li le li-anilog tsa monoglycerides, li-progerrades le phospholilids, ha li ntse li hokahantsoe le mohatla o habeli.
4.4 Ho latela mofuta oa sehlopha sa hlooho
①Canic AAS
Sehlopha sa hlooho sa mofuta ona sa sirfacant o na le tefo e ntle. AAS ea pele-pele e be ethyl cocoyl e pharalletseng, e leng pyrroline carboxle. Litlhoko tse ikhethang le tse fapaneng tsa sejalo tsena li etsa hore le li etse thuso ea likotlo, li-agente tsa lithibela-mafu, baemeli ba moriri, hammoho le ho ba bonolo mahlong a borikhoe. Sina re na le li-as tse nang le li-aic tse sebetsang tsa asginine le ho tiisa thepa ea tsona ea mmele. Thutong ena, ba ne ba nka hore lihlahisoa tse ngata tsa lihlahisoa tse fumanoeng ba sebelisa maemo a boiketlo ba bo-ileng ba fetoha. Ka bolelele ba alkyl Chain le hydrophobicity, tšebetso ea sebaka se phatsimang e ile ea fumanoa ho eketseha le ho ba le litoeba tse nyarosang (cmc) ho fokotseha. E 'ngoe ke protheine ea quaterry e acinyl, e sebelisoang e le setsebi sa lihlahisoa tsa tlhokomelo ea moriri.
②unionic AAS
Libakeng tsa li-Anionic, sehlopha sa hlooho sa polar se sephara se na le tefo e mpe. Sarcosine (Ch 3-C CH 2-CH 2-BO 2-METHYLGLCYCINE), Amino acid e fumanehang ho li-glycine (nh 2 -ch amino amino amino antino a e fumanoang liseleng tsa maismona. -Cooh,) Na lik'hemik'hale li amana le glycine, e leng acid ea motheo e fumanoang lisele tsa mahemmari. Lauric acid, tetradecanoic acid, oleic acid le li-hasteri tsa eona le li-eleithara tsa eona tse tloaelehileng ho hlahisa li-surcsatante tse kholo. Ho roala ka tlhaho ebile ha ho bonolo ho sebelisoa ka molomo, shampoos, litlolo tsa letlalo le lihlahisoa tse ling tsa letlalo le lihlahisoa tse ling tsa likereke.
Tse ling tsa Anisoc AAS li kenyelletsa Amosoft CS-22 le Amilitegck-12, e leng mabitso a khoebo bakeng sa Sodium N-Cocoyl-L-glutamate le Pocayl glycinate Amolite o sebelisoa e le moemeli ea thetsang, sesenthimithara, embofifier, a le lihlong, a hlatsoa litlolo, o hlatsoa litlolo le mabota a marang-rang. Amisoft e sebelisoa e le letlalo le bobebe le lesapo la moriri, haholo-holo ka sefahleho, lihlahisoa tsa tlhokomelo ea mmele, lihlahisoa tsa tlhokomelo ea mmele, li-shampoos le lihlahisoa tse ling tsa tlhokomelo ea letlalo.
③zwricionic kapa Amphoctic AAS
Libaka tsa bongaka tsa Amphoratoni li na le acidic le tsa mantlha ka tsona li ka fetola tefo ea tsona ka ho fetola boleng ba PH. Ka har'a li-arifine tsa alkaline ba itšoara joaloka marulelo a anionic, ha ba ntse ba le maemong acific, ba itšoara ka litlolo tse mpe tsa acichoteric. Lauryl Lysine (ll) le Alkoxypropyproppyl) ho tsoana Ll ke sehlahisoa sa Lysine le Lauric acid. Ka lebaka la sebopeho sa eona sa bolulo, ll o sa khathatse hoo e batlang e le mefuta eohle ea li-solvents, ntle le li-albsne kapa li-acidic solvent. Joaloka phofo ea manyolo, ll e na le moea o motle oa hydrophilic ho hydrophilic libakeng tsa litlolo le likhohlano tse tlase, tse fanang ka bokhoni bona bo tlokotsi. Ll e sebelisoa haholo ka liseleng tsa letlalo le batho ba moriri oa moriri, 'me e boetse e sebelisoa e le lubricant.
④nonic AAS
Li-surficants tse neng li sa ratehe li tšoauoa ka lihlopha tsa polokelo ea polar ntle le liqoso tse hlophisitsoeng. Li-surficer tse robeli tse sa lumellaneng tse neng li hlophisitsoe ke Al-Sabagh et al. ho tloha ho tloha ka oli -mino acid. Ketsong ena, L-Phenyanine (Lep) le L-Leucine e ile ea emisoa ka Hexadecano, e lateloang ke mohoebi ea babeli le ba babeli ba li-acide tsa α-emis. Ho lula le ho lula le ho feta ha ethylene. Li-AAS tsena tse sa lumellaneng li ile tsa fumanoa li na le maemo a matle le thepa e litšila.
05 Synthesis
5.1 Motsamao oa mantlha oa maiketsetso
Ho AAS, lihlopha tsa hydrophobic li ka hokahantsoe le libaka tsamine kapa carboxylic acid acid, kapa ka liketane tse mahlakoreng a Amino acid. Ho latela sena, litsela tse 'ne tsa maiketsetso tsa maiketsetso lia fumaneha, joalo ka ha ho bontšitsoe ho Setšoantšo sa 5.
Litekanyetso tsa mantlha tsa fig.5 tsa li-amino acid-acid tse thehiloeng ho life
| Tsela ea 1. Mahana a amppehlilic a hlahisoa ka maikutlo a ho ts'oaroa, moo hangata a fumanoang ka mokhoa o tloaelehileng o fumanoang ka mafura le acid ea moemeli le acidic e holofetseng. Maemong a mang, sebabotho sa sulfuric acid e le 'mino oa kananelo le moemeli ea sa hlakang.
Pathway 2. Amino acid e hlahisoang ke alkkhings ho etsa li-amideme tsa sebaka, ho etsa hore li-amithesis of amphhilic antitrahis of amphhilic aidomines.
Tsela ea 3. Amiducid e etsoa ka ho araba lihlopha tsa linaha tsamines tsa Amino acid.
Pathway 4. Long-Chain Amkyl Acino Acino o ne a hokahane ke karabelo ea lihlopha tsa Moomane tse nang le haloal. |
5.2 Tswelopele ho Syntthesis le tlhahiso
5.2.1 Synthes of Anino Acino Acino Acino Acino acid / Peteride Surfactats
N-Acyl kapa O-Acyl Acino acino acino acino acidi Litšoantšo tsa pele-pele ka li-synthes tse sa sebetseng hantle tsa Amino acide Methyl Ethyl ea Ethyl ea Ethyl e boetse e sebelisoa e le solvent maemong a mang. Vundergen et al. E boetse e hlalositse mekhoa le litheko tsa imposes tsa li-amino acids, protein hydrolysates le / kapa li-sorivors tsa metsi le li-solthyolmamide / metsi) le methyl buyl.
Matsatsing a pele, bothata bo ka sehloohong ba maikutlo a enzyme-e ne e le chai e tlase haholo. Ho latela Valvivety et al. Lipokoi tsa N-Tetradecannayl amino acily e ne e le 2% feela -10% le kamora ho iphuthusa ka 70 ° C ka matsatsi a mangata. Montet et al al. E boetse e na le mathata a amanang le chai e tlase ea Amino acis acine e sebelisang mafura le oli ea meroho le oli ea meroho. Ho ea ka bona, chai e phahameng ea sehlahisoa e ne e le 19% tlasa maemo a sa lefelloeng le ho sebelisa li-solvent tsa khale. Bothata bo tšoanang bo ile ba kopana le VIGIVIVIVETY Et al. in the synthesis of N-Cbz-L-lysine or N-Cbz-lysine methyl ester derivatives.
Thutong ena, ba ne ba re seithuti sa 3-T-Tetradecanoyl-l-segine e ne e le 80% ha e sebelisoa Setopo se sirelelitsoeng tikolohong e se nang molte. Nagao le Kitto ba ne ba ithuta O-Setsebi, L-Hosene, L-Homolenine, L-Homonine Achlongtion ea T-o sokele mme o ketekoe.
Bafuputsi ba bangata ba bontšitse tšebeliso ea theko e theko e tlaase 'me ba fumaneha habonolo joalo ka li-sonothe tse nang le chelete e ngata. Soo et al. Ba boletse hore ho hlophisoa ha lijalo tse ahiloeng ka oli ea Palm tse sebetsang hantle le lipoenbolized liponzlized. Ba hlokometse hore tlhahiso ea lihlahisoa e ka ba betere leha e le nako ea ho etsa karabelo (matsatsi a 6). Gerova et al. Ba fuputsa ketsahalo ea Synthesis le bokaholimo ba sebaka sa chira n-palmitomy e ipapisitse le methionine, e sokelang phenya le phenylglycine motsoako oa cyclic / peiso. PANG LE CHU li hlalositse li-synthes tsa bakuli ba amino acidboxxy e thehiloeng tharollong le likhang tsa poldedradadadadation ka tharollo.
Cantaezene le Guerreiro li ile tsa tlaleha hore batho ba hlomphuoang ba boc-ah le Boc-asp -. Thutong ena, karabelo ea Boc-Ala-oh 99.9%) Ho hlahisa li-chai tse 58% ho isa ho 76%, e neng e thibetsoe ka li-alkyhols tse fapaneng ka CBZ-Arg-Ome, moo papa e neng e le ka sebetsa e le sekoti.
5.2.2 Synttheis tsa Amino acid acid / Peteride Surfital
Li-amino acid-acid tse thehiloeng ho amino acid li na le limolek'hule tse peli tse otlolohileng tse hokahaneng hloohong. Ho na le merero e ka bang 2 ka lits'oants'o tse peli tsa li-chemoenzymatic Synthermis ea li-amino acily tse thehiloeng ho gramini acid. Setšoantšong sa 6, li-amino atino acino acid li sebelisoa le komporo ea spacer le lihlopha tse peli tsa hydrophobic li tsebisoa. Setšoantšong 7, meaho ea 2 ea litulo tse otlolohileng e hokahantsoe ka kotloloho ke sehlopha sa sethala sa sepakapaka.
Litšoantšo tsa pele-pele tsa enzyme-Catalyzde Synthes ea Gemini Lipoamino Acid e ile ea ba pula-maliboho ka Valvivey et al. Yoshira et al. Batlisitsitlo The Amino Amino acid e ipapisitse le Surfital e thehiloeng ho Amino acid e thehiloeng ho cystinine le n-alkyl bride. Ho ne ho bapisoa le likotsi tsa limela tse lumellanang ho bapisoa le li-surfachoane tse tsamaeang le li-monome. Fausno o batla al. e hlalositse li-syntthes tsa li-anioni tsa Ananic Urea, L-methionine le sebopeho sa metsi a lekanang le a tsitsitseng. E bontšoa hore boleng ba cmc ba Gemini bo ne bo le tlase ka ho bapisa Monotor le Gemini.
Synthes ea geg.6
Fega.7 Synthes ea A 27 Ass ass a sebelisa sepakapaka sa Bifunc tir le AAS
5.2.3 Synthes of Glycelipid Acinolidid Acino acid / Peteride Surfactats
Glycelitedid atinolilipid atino acid / Peteide Synthes ea litsi tsena e qala ka ho hlophisoa ha li-amino acidratirator le boteng ba catalyc catalyst (mohlala, bf 3). Enzyme-catalyzed Synthesis (o sebelisa hydrolases, li-insemes le litsela tse kang li-catalysts) hape ke khetho e ntle (Setšoantšo sa 8).
Synthes ea enzyme ea anzyme ea argine e hapiloeng a rema papa e tlalehiloe. Synthesis ea lefu la lefu la diacyglycerol e kopanya le ho lekola thepa ea bona ea physochemical le eona e tlalehiloe.
Fig.8 Synthesis ea Mono le Diacylglycerol Acino acid e kopanya
Spacer: NH- (CH2)10-NH: komporo ea komporo
Spacer: nh-c6H4-NH: komporo
Spacer: CH2-Ch2: khomphutha ea komporo
FOG.9 Synthesis ea Symmetric Amppeshiles e tsoa ho TRIS (HydroxyMethyl) aminomethane
5.2.4 Synthesis ea Amino acid / Peteride Surfactats
Amino acid-the thempipho e thehiloeng ho Amino acipets e na le li-amino acid tse peli tse amanang le ketane e tšoanang ea hydrophobic. Franceschi ebang al. Sekhahla sa mofuta oa mofuta oa Bola-mofuta oa 2 Amono a Alanine kapa l-hist of bolelele ba bona. Ba buisana ka syntthes le boima ba mofuta oa li-novel bola-mofuta oa amino acid (o sebelisa joala bo sa tloaelehang. Motho ea sa tloaelehang β-Acino amid a ka ba aminoacid, azt, amino atino atino atino atino amino amino atino atino amino amid, le joala ba 9). Synthesis of Symmetrical Bola-mofuta Amppergiles Ditm (HydroxyMethyl) AminoMathane (TRIS) (Setšoantšo sa 9) (Setšoantšo sa 9)
06 LITLHAKISO TSA BOPHELO
Ho tsebahala hore lintho tse sa tloaelehang tsa Amino acid li fapaneng le tse fapaneng tsa tlhaho le ho ba le ts'ebeliso e ntle lits'ebetsong tse ngata le ho hanyetsa metsi a mangata (calcium ion).
Ho ipapisitsoe le thepa e potolohileng ea Amino acid (mohlala, ho ile ha fifatsoa boitšoaro le mocheso oa marapo.
6.1 LITLHAKISO TSE KHOLO TSE KHOLO (CMC)
Ho tsepamisa likelello tsa bohlokoa tsa litoeba tsa bohlokoa tsa mofuta oa li-surfades le ho sebelisana le selefouno, ka hona, eketsa ketsahalo ea eona cmc ea cmc. Li-surfactant tse thehiloeng ho Amino acid li na le boleng bo tlase ba CMC ha li bapisoa le li-surfachoak tse tloaelehileng.
Ka mefuta e fapaneng ea lihlopha tsa hlooho le meharo ea hydrolobic (Mookameli oa Hydrophobic (Mono-Innticemice li-as tse tharo tse thehiloeng ho li-as tse amanang le li-as tse amanang le li-as li ipakile li le cmc le γcMC (boleng bo teba ka cmc le γcM Thutong e 'ngoe, ho rata' meleng, 'mala o fumane hore cmc ea li-lydrolonine e fokotsehile ka ho eketsa liathomo tsa khase ea hydrophobic ea hydrophobic (tafole 1).
Yoshira et al. E fanoe CMC ea Li-Amino Acino Acino Acino Acino a fokotseha ha bolelele ba carbonchic bo ile ba eketseha ho tloha CMC, bo ileng ba tiisa hore litulo tsa litulo tsa konkrophobic li eketsehile ka mokhoa o tlase oa ho kenyelletsa.
Fausno o batla al. ho tlaleha sebopeho sa li-mice tse fapaneng ka tharollo ea aequous ea surftants tsa Anionic tse thehiloeng ho cystine. Li-surfonnita tsa gemini li ne li bapisoa le litlolo tse tsamaeang ka mokhoa o tšoanang oa limpho (C 8 cys). Melao ea metsoako ea cmc ea lipid-surftancia e tlalehiloe e le tlase ho feta ea li-surfacal tse hloekileng. Gemini Surfactats and 1,2-DihePaniyl-Sn-Glyceryl-3-PhoSphoCiple
Shrestha le Aramaki ba ile ba etsa lipatlisiso ka mofuta oa li-micelestala tsa Viscoelas tsa Viscoelastic ka tharollo ea mahe a antianguc-e neng e sa ratehe ka har'a li-aicinic. Thutong ena, N-Dodecyl Glutamate e ile ea fumanoa e ba le mocheso o phahameng oa kura; Leha ho le joalo, ha o sa tiea le Amino Acino Acino o hlahisitse litlolo le tharollo e qalile ho itšoara joaloka mokelikeli oa khale ka 25 ° C.
6.2 Sleloudity ea Metsi ea Metsi
ALDUBE ea metsi e ntle ea AAS e bakoa ke boteng ba litlamo tse ling tsa co-nh. This makes AAS more biodegradable and environmentally friendly than the corresponding conventional surfactants. Sello sa metsi sa metsi a n-Acyl-l-glutamic acid e molemo le ho lihlopha tsa eona tsa carboxyl. Chelete ea metsi ea CN (CA) hape e ntle hobane ho na le lihlopha tse peli tsa li-ionine le lithibelo tse sebetsang ka thata.
6.3 Krafft Mocheso le Krafft Point
Mocheso oa Krafft o ka utloisisoa joalo ka boitšoaro bo ikhethang ba li-surfactity tsa bona tsa li-surfactant tseo tharollo e phahamisang ho feta mocheso o itseng. Li-surfactats tsa ionic li na le tloaelo ea ho hlahisa li-hdrautes tse sa tiisetsa, tse ka ho koloba ka metsi. Ka mocheso o itseng (eo ho thoeng ke mocheso oa Krafft), keketseho e makatsang le e sa khaotseng ea solububle ea li-surfactats hangata e hlokomeloa. The Krafft Point ea silika ea iinic ke mocheso oa eona oa Krafft ho cmc.
Mofuta ona oa alloubility o bonoa bakeng sa li-surfsants tsa ionic mme li ka hlalosoa ka mokhoa o latelang: Monotor oa Surfft flang o eketsoa ka tlase ho mofuta oa micelle. Ho etsa bonnete ba hore alloubility e felletseng, ho hlokahala hore o lokise merero ea potoloho ea mocheso ka holim'a ntlha ea Krafft.
Mocheso oa Krafft oa li-AAS o ithutile le ho bapisa boits'oaro bo boholo ba 'mele bo boholo ba mepere N-Hexadecanoyl AAS mme a buisana ka kamano e teng lipakeng tsa mocheso oa bona oa Krafft le atino acid masala a mane.
Litekong, ho ile ha fumanoa hore mocheso oa Krafft oa N-Hexadecanyl Acility (Phello ea Heard) e eketsehile ka boholo ba Amino acine le phenyanine). E ne e le qeto ea hore ka mekhoa ea alane le ea phenyanine, tšebelisano ea DL e matla ho feta tšebelisano ea ll ka sebopeho se tiileng sa n-hexadecanoyl as.
Brito et al. Iketsetse mocheso oa Krafft oa likoto tse tharo tsa li-amino amino amino a sebelisa karolo e fapaneng ea li-microcalorromation. Ho ba teng ha maqhama a boxy le ho se fetohe hona joale ho feto-fetoha ha nako N-Dodecyl Glutamate e tlalehiloe hore e na le mocheso o phahameng oa kupa. Leha ho le joalo, ho se nke lehlakore ka li-amino acino acidle ka lebaka la ho etsoa ha litoene ka tharollo e amanang le maro a ncha a fetileng a 25 ° C.
6.4 Ho tsitsipana ka holimo
Ho tsitsipana ha bokaholimo ba liphoofolo ho amana le bolelele ba ketane ea karolo ea hydrophobic. Zhang et al al. A tiile tsitsipano ea bophara ba sodium cocoyl gelycinate ka mokhoa oa hau oa Wilhelmy (25 ° C.2) ° C.2) ° C.2) ° C.2) Yoshira et al. O ile a tiea tsitsipano ea bokaholimo ba 2c N Cys mofuta o nang le metsi a holimo a amino acino acid ea lefatše la 2c n cys Ho ile ha fumanoa hore bokaholimo ba bokaholimo ba cmc bo fokotsehile ka bolelele bo ntseng bo eketseha (ho fihlela n = 8), bolelele ba liketane.
Liphello tsa Cac1 2 tsietsing e holim 'a li-amino aminoclants e ithutileng li ithutile. Lithutong tsena, Cac1 2 e ile ea eketsoa tharollo ea amingboxylated Amino atino amid-mofuta oa mofuta oa Amino Acingo 2, C12 Gluna 2). Lithethara tsa thota ka mor'a cmc li ne li bapisoa le moo ho fumanoe hore tsitsipano e fokotsehileng haholo meaho e tlase ea cac1 2. Sena se bakoa ke phello ea li-calcium ions torong ea sethala sa mofuta oa khase. Boholo ba letsoai la letsoai la N-Dodecylaminoate le N-Dodecylate, ka lehlakoreng le leng, le bona ba batla ba le ho 10 mmol-l -1 cac1. Ka holimo ho 10 MMOL-L -1, likhohlano tsa bokaholimo li eketseha haholo, ka lebaka la ho thehoa ha pula ea letsoai. Bakeng sa letsoai la sejo sa N-Dodecyl, kenyelletso e itekanetseng ea Cac1
Ho fumana hore li-assotic killics tsa li-aas tsa mofuta oa Gemini, ho ne ho ikemiselitse ho sebelisa mokhoa o phahameng oa khatello ea maikutlo. Liphello li bonts'a hore ka nako e telele ka teko, palo ea mano a mabeli a cys e nang le matla a mapolanka a ho nyoloha ha a sa fetoha. Ho fokotseha ha tsitsipano ea lefatše le matla ho latela feela mahlorisong, bolelele ba mehatla ea hydrophobic, le palo ea mehatla ea hydrophobic. Ho eketseha ha lefatše la ho pharalla ha sebaka, bolelele ba kenyane hammoho le palo ea liketane e ile ea bola ka potlako le ho feta. Liphetho tse fumanoeng bakeng sa leihlo le phahameng la C N CYS (N = 8 ho isa ho 12) li fumanoe li le haufi haholo le SMC e lekantsoeng ke mokhoa oa WILHELI.
Phuputsong e 'ngoe, likhohlano tse matla tsa sodium dilauryl cystine (Sdlc) le mokhoa oa poleiti oa mapolanka oa mathata a bona a neng a putlama. Boitšoaro ba maqhama a phefumoloho bo ile ba etsoa lipatlisiso ka mekhoa e meng hape. Katsetso ea mercaptonaol ho isa ho la 0,1 MMOLL ho ile ha eketsa ka lebelo le potlakileng maemong a holimo ho tloha 34 mn-m -1. Kaha Noto a ka hlakola litlamo tsa ho senyeha ha SDLC ho lihlopha tsa Sulfonic li ile tsa bonoa ha napelo (5 mmol-l -1 sdlc tharollo. Ho ile ha bontšoa phetiso ea elektrone le liphetho tse bobebe tse sa tsitsang tse bontšitsoeng hore ha ho na lingaka tse bonoang ka tharollo. Ho fumanoe meroalo ea holim'a SDLC ea SDLC ea SDLC e tsoang ho tloha ho 34 mn-m -1 ho 60 mn-m -1 nako e fetang 20 min.
6.5 GINARERTIONS
Mahlale a Phelo, lihlopha tse 'maloa li ithutile thepa ea vibral ea li-vibral ea li-suric AAS (qetellong ea diacylglyce) le phospholilids ka har'a thepa e sa tšoaneleheng ea khase.
6,6 Properties ea Aggregation
Leseli le bobebe la matla le se le tloaetse ho khetholla thepa ea aminore ea Amino acid le Geminic Doometer Dh (= 2r h). Li-aggōgs tse thehiloeng ke C N Cys le Cys tsa 2cn li bohlokoa ebile li bapisoa le li-surfyal tse ling. Li-surfactats tsohle ntle le li-cys tsa 2c hangata hangata li etsa li-aggreg tse ka bang 10 nm. Mefuta ea li-michelle ea litoeba tsa Gemini e kholo haholo ho feta ea limoleric tsa tsona tsa botona. Keketseho ea bolelele ba ketane ea hydrocarbon le bona bo lebisa keketseho ea boholo ba Medelle. Ohta et al. E hlalositse thepa e meraro ea li-stereosimmers tse tharo tse fapaneng tsa li-N-Dhenyl-bichenyl-tšoaokllimin Iwahashi et al. E fanoe ke khatello ea maikutlo ea mamati a NMR 1,2-dichlloroethane) e nang le thepa e potolohileng e hlahlojoa ka khatello ea kelello ea NMR le Dapor osmometry.
6.7 Adsorption ea Intermacial
Ho latela mokhoa oa ho sebelisa li-amino Acino o thehiloeng ho amino acid le molekane oa eona oa tloaelo ebile ke e 'ngoe ea tsela ea lipatlisiso. Mohlala, thepa e sa lekaneng ea ho khella li-amino e atisang amino acid a acinotic e fumanoang ho tloha ka matsoho le leoto li ile tsa hlahlojoa. Liphetho li bontšitse hore le Lep li bonts'a libaka tse sa sebetseng hantle tsa khase le setene sa metsi / Hexane, ka ho latellana.
Borde et al. Batlisitsitše boitšoaro ba tharollo le ho rema masela a 'mala oa khase ea Aminocixylated Amino acid, le aminomalonate (ka 3, ka ho latellana). Ho latela tlaleho ena, cmc ea limela tse dirong e ne e le 4-5 ka linako tse ling tse phahameng ka linako tse ling tse phahameng ka linako tse ling letsoai la monocarboxne. Sena se hlahisoa ke sebopeho sa maqhubu a hydrogen pakeng tsa likotlo tse mpe le limolek'hule tsa boahisani ka har'a lihlopha tsa moahomaneng.
6.8 Botsha
Likarolo tsa li-cubic tse hlahisoang ke li-cubic tse hlahisoang ke li-cubic li bonoa bakeng sa li-surfactats tse kholo haholo. Limolek'hule tsa limela tse nang le lihlopha tse kholo haholo tsa lihlooho li tloaetse ho etsa hore li tsebe ho bakoa ke bakolli bo monate. marque et al al. e ithutileng boits'oaro ba li-12lys12 / 12ser le tsamaiso ea maikutlo a 8lys8 / 16ser sebaka sa maqephe). Re lokela ho hlokomela hore bakeng sa sebaka sa Vesicle12 / 12ser, li-afsicles li lula li le haufi le li-micelles tsa li-vesicles tsa 8lys8 / tse 16ser.
Metsoako ea Catanionic ea li-gracianicer tsa li-lysine- le tsa sermmetri li thehiloeng: "Symmetric12
6.9 Bokhoni bo matlafatsang
Kouchi et al. Lekola bokhoni bo matlafatsang, tsitsipano ea ho lieha, ho fokola le ho bonahala eka ke pono ea "3-DodecylpropyproPypropinyl] -l-glutamate le li-as tse ling. Ha a bapisoa le li-syfsants tsa synthetic (libapali tsa bona tse sa fetoheng le tsa Amphote
Baczko Et al. Li-syrethesides Novel Aniinic Acino acino acino acid le tse fuoeng lisosa tsa bona tsa chira tse amanang le sebaka sa nmma sperts Letoto la setutho sa sulfnate-they heng kapa L-Alavitas Wu et al. Lijo tsa sodium tsa sodium tsa n-fatty asyl as leBa Hlakisetsa bokhoni ba bona ba ho tsuba ka oli, 'me lipheo tsena li bonts'a hore li-surfanga tsena li phehoa hantle ka Ethyl Acetate e le karolo ea oli.
6.10 Khaolo ea Khauta ea Synthes le tlhahiso
Ho hanyetsa ha metsi ho ka utloisisoa joalo ka bokhoni ba ho hanela ho ba teng ha li-ii ha a hanela ho ba teng ha li-ii ha a hanela ho ba teng ha calcium le magnesiun ka metsing a thata. Li-surfactant tse nang le litlolo tse ngata tse nang le metsi a mangata li bohlokoa haholo bakeng sa lipalo le lihlahisoa tsa tlhokomelo ea motho. Khanyetso e thata ea metsi e ka hlahlojoa ka ho bala phetoho ea phetoho ea lillo le ka ho fetisisa ea ho pharalla ha mmila o teng.
Mokhoa o mong oa ho lekola tšitiso ea metsi a thata ke ho bala liperesente kapa ligrama tsa sistimo e thehiloeng ho tloha ka 100 g ea sodium e lokelang ho hasanngoa ka metsi. Libakeng tse nang le metsi a mangata a thata, meaho e phahameng ea calcium le litaba tsa liminerale li ka etsa hore ho be thatafalloa ke likopo tse sebetsang. Hangata Ion ea Sodium e sebelisoa e le 'mino oa li-synthetic tsa maiketsetso. Ho tloha ha calcihle ea khethollo ea limolek'hule e tlameletsoe limolek'hule tse ling tsa limela, e etsa hore sere se be bonolo ho ba hloma monyetla oa ho etsa joalo.
Ho ithuta ha libaka tse thata tsa Aa ho bonts'a hore lisiti tse ngata li ne li susumetsoa ka matla ke molao-butle o mong oa carboxyl ho feta lihlopha tse peli tsa carboxyl. Tlhophiso ea asiti le khanyetso e thata ea metsi e ne e le c 12 glycinate <c 12 aspartate <c 12 glutamate. Ha ho na moondi ea neng a le kotsi a tloaelehileng le sebaka se litšila sa aminoxart, ka ho latellana, ho ile ha fumaneha hore malinyane a morao a ne a sentse a leketlile le ho eketsoa ha asiti. Moetsi oa li-dicarboxylated Acino o atino acid o bontšitse ho hlahloba boteng ba calcium ions, le C 12 aspartete e thehiloe gel e tšoeu e thehiloeng. C 12 glutamate e bonts'a tšebetso e phahameng ea ho hlasimoloha ka 2+ mme e lebelletsoe ho sebelisoa ho isa ho metsi a leoatle.
6.11 ho senyeha
Ho senyeha ho bolela bokhoni ba ho phatloha ho thibela binalescence le seditual of the sistimi ka tharollo.Ho se khonehe ke thepa ea bohlokoa ea lijalo tse etsang hore li se ke li loketse ho sebelisoa ka seriti, litlolo le meriana ea meriana.Moemeli ea hasang o tlameha ho ba le ester, ether, tlamo ea tlhaho ea lebitso le sehlopha sa hydrophobic (kapa har'a sehlopha sa Chain hydrophobic).
Ka kakaretso, simfatso ea litsi tsa Anionic e kang Alkanolamido e joalo ea Alkanolamido e kang Amisoslutle e sebetsa haholo joalo ka li-foaps tsa calcium.
Boiteko ba Bangata ba lipatlisiso bo ile ba sebeletsa ho se lahlang AAS, moo L lysityl Lysine e neng e fumaneha hampe ka metsi mme e thata ho e sebelisa bakeng sa lifono tsa boselamose.Letotong lena, Amony-acid e nkileng Amono acino a na le kahlolo e molemo le e sebelisoang indastering ea litlolo ho ntlafatsa liforomo.
07 chefo
Boholo ba liphoofolo tse tloaelehileng, haholo-holo lijalo tsa maikutlo, li chefo haholo ho likokoana-hloko tsa metsing. Ho chefo ka matla ha bona ho bakoa ke mohlala o bakiloeng ke ho hlaheloa ke tlhekefetso ea Adfordown ea lijo-thollo tsa metsi a selefouno. Ho fokotseha cmc ea lijalo tse mpe hangata ho lebisa ho thetso e matla ea ho apa, e fapaneng ho eona e phahamisa chefo e mpe e mpe. Keketseho ea bolelele ba hydrophobic e lebisang keketseho ea limela tse silafatsang limela.Boholo ba MaAs ha ba na mahlo kapa ba sa chefo ho batho le tikoloho (haholo-holo ho li-Kopishene ea Marine) 'me li loketse ho sebelisoa e le metsoako ea lijo, meriana le litlolo.Bafuputsi ba bangata ba bontšitse hore li-acictad tsa Amino acid li bonolo ebile ha li khopisoe letlalong. Li-surfada ba phetisetso tse thehiloeng bo thehiloeng bo fapaneng li tsejoa li se na chefo ho feta kamoo e leng mangolo a tloaelehileng.
Brito et al. Ho ne ho thulana le thepa ea maiketsetso le e nang le litlhaku tsa amino acig. Li hlahisa majoe a nang le a dodelylathmoniumbmonium ea breab ea bona mme a leka ho fokola ha as le docesiccles.
Rosa et al. fuputsa tlama (setsoalle) ea DNA ho ea ho ba nang le li-acino tse katiloeng ka naha e loketseng. Ho fapana le litšitiso tse tloaelehileng tsa maandani, tseo ho bonahala eka li na chefo, tšebelisano ea mathata a ameheic ho bonahala e se na chefo. Mana a candic a ipapisitse le maqhubu, ao ka ho itlhahisa a etsa li-avecles tse tsitsitseng tsa ho kopantsoe le litsietsi tse itseng tse fapaneng. Litsie tse thehiloeng ho amino acig. Li-surfactats tsena tse litopo li tsamaisoa habonolo ka bohloeki bo phahameng (ho fihlela ho 99%), litšenyehelo tse tlase, tse theko e tlaase ka ho fetisisa ho li-biodegraphy. Boithuto bo 'maloa bo bontšitse hore li-sulfur-atino acid li-surfactats tse phahameng li phahame haholo ho thibelo ea lijalo.
Thutong ea morao tjena, Perlinelli et al. ho tlaleha boemo bo khotsofatsang ba ho chefo ba li-rihamnoliids ha ba bapisoa le li-surfachoak tse tloaelehileng. Rihanolipids e tsejoa e le li-emthancers tse ntle. Ba boetse ba tlaleha phello ea Rihamnolied mabapi le ho nepahala ha lithethefatsi tsa marromoleculacular.
08 Ketsahalo ea Khalemelo
Ketsahalo ea likokoana-hloko e ka hlahlojoa ke ho tsepamisa maikutlo a tlase. Ketsahalo ea sengoathoana sa li-surfata e thehiloeng ho adrinine e ithutileng ka botlalo. Baktheria e mpe e fumanoe e hanyetsanang le ho feta ho li-ntloana tse thehiloeng ho gragine ho fapana le ho Gram-hantle libaktheria. Ketsahalo ea likokoana-hloko ea li-surfactats hangata e eketsoa ke boteng ba Hydroxyl, li-cyclocroproproproproproproproproproproproproproproproproproproproproproproproproproprope kapa litlamo tse sa tsitsang ka har'a liketane tsa Ainyl. Castillo et al. e bonts'a hore bolelele ba liketane tse aheletsoeng le tefo e ntle li lekola boleng ba HLB (sydrophilic-lipophilic-lipophilic bokhoni ba bona ba ho senya litho tsa bona tsa kelello. Ncy-acylargines Methyl Esterster ke sehlopha se seng sa bohlokoa sa ho ts'oaroa ha ameriki le ka mokhoa o hlakileng ebile o na le chefo. Boithuto ba 'mabollo a Ncy-Acylar-Lithyl Ester Litšitiso li bontšitse hore sehlopha sena sa limela se bonts'a litholoana tse ntle tse bonts'ang hore li-surfacal li na le ts'ebetso e ntle ea likokole.
09 Runogical thepa
Merusu ea li-torgacoloctors e bapala karolo ea bohlokoahali ho tseba le ho etsa lijo, meriana, meriana, meriana, liphallelo tsa oli le lihlahisoa tsa tlhokomelo ea hae le batho ba tlhokomelo ea hae le lihlahisoa tsa tlhokomelo ea hae le tsa tlhokomelo ea tlhokomelo le lapeng. Ho entsoe lithuto tse ngata ho buisana ka kamano pakeng tsa Viscoelalation of Amino acid surfactats le cmc.
Likopo tse 10 ka indasteri ea litlolo
Li-AA li sebelisoa ho lihlahisoa tse ngata tsa tlhokomelo ea motho.Potasiam h-cocoyl glycinate e fumaneha letlalong 'me e sebelisoa ho itlhoekisa le ho tlosa ho thekesela le litlolo. N-ACYL-L-Glutamic acid e na le lihlopha tse peli tsa carboxyl, tse etsang hore e qhibilihe ka metsing. Har'a libaka tsena, Maas ho latela li-acid tse 12 tse mafura ho sebelisoa haholo ho li-acid tse tlhoekiso ea sefahleho ho tlosa mohloa le litlolo. Li-AAA tse nang le lijana tsa C. li sebelisoa e le mafura a tlhokomelo ea letlalo, 'me letsoai alane a tsebahala ka letlalo mme ka nako eo a ka sebelisoa ho lihlahisoa tsa tlhokomelo ea bana. Mahala a The AAS a sebelisitsoeng ho meno a meno a na le boemo bo botle bo nang le botsitso bo tšoanang le sesepa le katleho e matla ea enzyme.
Lilemong tse mashome a seng makae tse fetileng, khetho ea litlolo tsa infmetics, lihlahisoa tsa tlhokomelo le mekhamaticals e tsepamisitse maikutlo a khahlano le chefo, bonolo, le polokeho ho ama le polokeho. Basebelisi ba lihlahisoa tsena ba tseba hantle ka ho teneha ka tsela e nyelisang, lintho tse chefo le tikoloho ea tikoloho.
Kajeno, li-AA li sebelisoa ho theha li-shampoos tse ngata, li-daes tsa moriri le litlolo tsa ho hlapela ka lebaka la melemo ea tsona e mengata ka li-cosmetics le lihlahisoa tsa tlhokomelo ea bona.Li-swein tse thehiloeng ho liprotheine li na le thepa e lakatsehang tse hlokahalang bakeng sa lihlahisoa tsa tlhokomelo. Maas a mang a na le bokhoni bo etsa lifilimi, ha ba bang ba ntse ba e-na le bokhoni bo botle ba boliso bo fofang.
Amino acid ke ea bohlokoa ke ntho e etsahalang ka tlhaho e etsahalang ka har'a lintho tsa stratum corneum. Ha lisele tsa tšoanche li shoa, e fetoha karolo ea lijalo tsa stumm tsa stum le lihlahla tse sa khaotseng butle-butle ho Amino acid. Ka hona, ba isoa ho ea fihla libakeng tsa sratum corneum, moo ba amohelang lintho tse nonneng kapa tse ngata ho epidermal sratum corneum, ka ho etsa joalo e ntlafatsa maqhubu a letlalo. Hoo e ka bang 50% ea ntho ea tlhaho ea tlhaho letlalong e entsoe ka Amino acid le pyrrolidone.
Motsoako o tloaelehileng oa litlolo, o boetse o na le acid acid ea amino a boloka letlalo le le bonolo.Mathata a letlalo a joalo, ho ba thata le ho thabe ha ho loketse karolong e kholo ea ho haella ha li-amino acid. Phuputso e 'ngoe e bontšitse hore ho kopanya amino antiang a nang le sebopeho se khopisitsoeng,' me libaka tse amehileng li ile tsa khutlela boemong ba tsona bo tloaelehileng ntle le hore ke be maqeba a li-sloid.
Amino acid le eona e fumanoe e le thuso haholo ho hlokomela li-cukecing tse senyehileng.Moriri o omileng, o se nang bofoko o ka supa ho fokotseha ha amino acid ka scutleum e senyehileng haholo. Amino acid e na le bokhoni ba ho kenella sehiloeng ka moqomong oa moriri le o monya mongobo letlalong.Bokhoni bona ba atino atino acid bo ba thusa haholo ho shampoos, li-daes tsa moriri, batho ba soma, le ho ba teng ha Amino acid ba etsa hore moriri o be matla.
Litšireletso tse 11 ka litlolo tsa letsatsi le letsatsi
Hajoale, ho na le tlhoko e 'ngoe e ntseng e hola ea ho etsa lintho tse senyehang ka lebaka la likhohlano tse thibetsoeng lefatšeng ka bophara.Makhopho a marang-rang a tsebahala ho ba le bokhoni bo botle ba ho hloekisa, bo boholo le thepa e makatsang, e etsang hore ba tšoanelehe ho litho tsa malapa, bo hlabisang lihlong, bosuli ba 'mele le likopo tse ling.Ha ho tlalehoe li-ampfic acid ea asPhoteric aspartic as acid Tšebeliso ea metsoako ea seriti e nang le acid a amid ea N-Alkyl-β-Aminothapon e fumanoe e ile ea fumanoa ho fokotsa ho halefa ke letlalo. Sebopeho sa thibelo ea metsi se nang le metsi a ho se sebetse hantle ha ho boletsoe ho ba sesepa se sebetsang bakeng sa letheba la oli libakeng tsa tšepe. Osid ea Aminocarboxycant e acid ea AMInocaxy
Ho hlophisoa ha mehopolo e sa tsitsang ho latela N- (N'-Long-Chain) -β-Alanyl) -β Kao o ile a theha ts'ebetso ea ho se bolokehe ho ipapisitse le N-Acyl-1 -n-alenine 'me a tlaleha ho halefa ka tlase, ho hana metsi a phahameng le ho tlosoa metsi a phahameng.
Khamphani ea Japane Ajinomoto e sebelisa Maas e nang le chefo e tlase le e senyehileng habonolo ea L-glutamic as ho Shampoos Bokhoni ba litla-morao tsa enzyme likhamareteng ho tlosa pherekano ea prothele e boetse e tlalehiloe. N-ACYL AAS e tsoa ho li-glutamic acid, Alanine, Methylcinecine Li-surfacript tsena tsa likonyana ha li eketse liketsahalo ho hang, esita le mocheso o tlase haholo, 'me o ka fetisoa habonolo ho tsoa sekepeng sa polokelo ho fumana foams tsa homoge.
Nako ea poso: Jun-09-2022